Vol 3, No 2 (2021)

A Systematic Review on Oral Lichen Planus: Pathogenesis and its Treatment

Authors: Krishna Dhungana, Sunil Gupta, Daisy Arora

Abstract: Oral lichen planus (LIE-kun PLAY-nus) is an ongoing (chronic) inflammatory condition that affects mucous membranes inside your mouth. Oral lichen planus may appear as white, lacy patches; red, swollen tissues; or open sores. These lesions may cause burning, pain or other discomfort. Oral lichen planus can't be passed from one person to another. The disorder occurs when the immune system mounts an attack against cells of the oral mucous membranes for unknown reasons. Symptoms can usually be managed, but people who have oral lichen planus need regular monitoring because they may be at risk of developing mouth cancer in the affected areas. The white, lacy patches may not cause discomfort when they appear on the inside of the cheeks. However, symptoms accompanying red, swollen patches and open sores may include burning sensation or pain. Some factors may increase your risk of developing oral lichen planus, such as having a disorder that lowers your immunity or taking certain medications, though more research is needed. In the present review a brief pathophysiology and different treatment approaches are discussed in brief.

Keywords: Oral Lichen planus, immunity, open sores, corticosteroids, nutraceuticles.

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